Formulation in Pharmacy Practice   2nd Edition

CLONIDINE
 
 
Clonidine hydrochloride is soluble 1 in 13 of water.  The BP injection has a pH of 4 - 7.

Formula

Clonidine 0.1mg per mL
 
Clonidine hydrochloride tablets 0.2mg 30   
Water (to mix to a paste) mL
Simple Syrup NF to to   60  mL
 
Expiry/Stability:  28 days.
 
Storage:  Refrigerate, preferably 4°C as per conditions of the study.
Protect from light.  Amber glass containers were used.
 
SHAKE BEFORE USE
 

REFERENCE
  1. Levinson M.L., Johnson C.E.  Stability of an extemporaneously compounded clonidine hydrochloride liquid.  Am J Hosp Pharm 1992; 49: 122-5.

 
Formulation in Pharmacy Practice
2nd Edition