Formulation in Pharmacy Practice   2nd Edition

DAPSONE
 
 
Dapsone is very slightly soluble in water and slightly soluble in alcohol.  Dapsone preparations may darken on exposure to light.

Formula A1

Dapsone Suspension 2mg per mL
 
Dapsone tablets 25mg 16   
Citric acid g
Water 50  mL
Syrup to   200  mL
 


Formula B1

Dapsone Suspension 2mg per mL
 
Dapsone tablets 25mg 16   
Ora-Sweet 100  mL
Ora-Plus 100  mL
 


Expiry:  30 days.
 
Stability:   Chemically stable for three months at 4°C and 25°C.
 
Storage:  Refrigeration recommended to reduce potential for microbial growth.  Amber plastic bottles used in the study.  Protect from light.
 
Shake well before use
 

 
REFERENCE
  1. Nahata MC, Morosco RS, Trowbridge JM.  Stability of dapsone in two oral Liquid dosage forms. Ann Pharmacother 2000; 34: 848-50.[PubMed Link]

 
Formulation in Pharmacy Practice
2nd Edition