An oral liquid made
from hydroxychloroquine will have an extremely bitter taste. No formal
stability studies have been located. If you are using the sulphate salt
this is freely soluble in water so there is no real need for a suspending
agent such as methylcellulose. A base of 40 % glycerol (sweet but no tooth
decay) and water with 0.1 % parabens could be used.
This simple mixture
can be added to the child's favorite drink immediately prior to administration.
A range of flavours could be tried in an attempt to make the mixture palatable.
There is also a formula in "Trissel's Stability of Compounded Formulations"
from an article by Pesko in Am Druggist 1993:207:57. A 50:50 mixture of
Ora-Plus and water was used for the base and a 30 day expiry date suggested
in the absence of stability testing.