Pyrimethamine is practically insoluble
in water, and slightly soluble in alcohol.
Formula
Pyrimethamine Suspension 2mg/mL |
| |
| Pyrimethamine Tablets 25mg |
40 |
|
| Methylcellulose Solution 1% |
250 |
mL |
| Syrup BP |
250 |
mL |
| |
|
Grind tablets to a powder. Add a little methylcellulose and syrup to form a paste. Add to volume. |
| |
| Expiry: 30
days. |
| |
|
Stability: Chemically stable for 91 days. |
| |
|
Storage: Protect from light in airtight containers. Refrigerate. |
| |
| Shake the bottle |
| |
|
|
|
REFERENCE
- Nahata M.C., Morosco R.S., Hipple H.T. Stability of pyrimethamine
in a liquid dosage formulation stored for three months.
Am J Health-Syst Pharm 1997; 54: 2714-2716.[PubMed
Link]
|