The solubility of ranitidine hydrochloride in water is about 660mg
per mL. An oral solution of ranitidine hydrochloride is
available in most countries, it contains ethanol 7.5% and parabens. The
injection has a pH of 6.7 - 7.3 and most formulations contain
0.5% phenol.
Commercially manufactured preparations are available in most countries and
should be used if possible.
Formula 1
Ranitidine 15mg per mL |
| |
| Ranitidine tablets 150mg |
10 |
|
| Water |
50 |
mL |
| Syrup |
to 100 |
mL |
| |
|
Expiry: 7 days |
| |
Storage: Refrigerate. Protect from light.
(The storage conditions were not mentioned in the study.) |
| |
|
Shake well before use |
| |
|
|
|
REFERENCE
- Karnes T.H., Harris S.R., Garnett W.R., March C. Concentration uniformity of
extemporaneously prepared ranitidine suspension. Am J Hosp Pharm 1989; 304-7.
|